So, D-aspartic acid benefits testosterone production… but how does DAA do this?

Or are we just going to take everyone’s word on everything here on the internet??

For the most part, DAA doesn’t directly stimulate testosterone production but instead does so through the Hypothalamus-Pituitary-Gonad (HPG) Axis.

Here’s a play-by-play of DAA’s testosterone-boosting bio-activities:[1,2]

  1. DAA stimulates the hypothalamus to release:
  2. GnRH, which in turn triggers the pituitary gland to secrete:
  3. LH and FSH, which respectively encourage the production of testosterone and sperm for an all-around boost on male sex hormone status.

Working from top (the brain) to bottom (the testes), DAA has a more regulatory role in testosterone synthesis, as opposed to outright boosting testosterone levels.

As a result, DAA is a relatively safer and healthier option, especially when consumed as D-aspartic acid calcium chelate (D-AA-CC) in minimally effective dosages.

But, even so, whether in DAA or D-AA-CC form, does the fact these this testosterone booster naturally boosts testosterone mean it’s a safe testosterone booster? Are there any potential downsides or side effects to taking D-aspartic acid for testosterone?

In this article, we’ll cover all the Pros and Cons of supplementing D-aspartic acid, as well as proper usage guidelines to taking DAA.

First, let’s start with the positives (i.e., the benefits) before tackling the negatives (i.e., the side effects). Which are, frankly, unlikely, considering that DAA is one of the safer natural testosterone boosters currently available.

D-Aspartic Acid Benefits (for Testosterone and More)

Primarily taken for testosterone boosting purposes, DAA’s T-boosting properties are fairly well-understood: DAA stimulates GnRH to trigger the pituitary secretion of FSH and LH, which increases testosterone production and secretion.

However, the benefits of increased testosterone secretion, as well as increased pituitary gland activity, are much broader than what many might expect.

With that in mind, the male health benefits of DAA supplementation include:[3,4]

  • Anabolic Muscle and Strength Gains: as the primary muscle-building hormone, testosterone plays a key role in muscle growth and development, making “natural T-boosting” of obvious interest to athletes and bodybuilders.
  • Sperm Quality: whereas LH stimulation encourages T gains, DAA’s effects on FSH may help improve sperm quality measures, such as sperm count, sperm morphology, sperm motility, and semen volume.
  • Cognitive Health and Performance: animal research suggests that, in addition to promoting testosterone status, DAA also seems to play a key role in neuronal development, assisting in the modulation of learning and memory.

Altogether, the combined benefits of DAA seem to amount to improved muscular performance, male fertility, and cognitive health.

DAA vs. D-AA-CC: Which is Better?

Typically the preferred form of DAA, D-Aspartic Acid Calcium Chelate (D-AA-CC) works similar to standard DAA, except that D-AA-CC comes bound to calcium chelate for improved absorption and overall bioavailability.

The increase in bioavailability allows D-AA-CC to work better in small dosages. Reducing the gastric side effects associated with D-aspartic acid while also lowering the risk of other side effects associated with high amounts of DAA.

How to Take D-Aspartic Acid?

How you take DAA depends on the DAA supplement.

High dosages of DAA require less frequent servings, often with a cycling requirement, whereas more moderate doses of DAA (especially D-AA-CC) may be safely taken more frequently.

For point of reference, here’s the “Suggested Use” directions for Testo Lab Pro®:

Take 4 NutriCaps® daily, preferably 2 in the morning and 2 in the afternoon/evening. For best results, Testo Lab Pro® should be taken consistently, as part of an overall fitness regimen including strength training and cardiovascular exercise.

These activities work in conjunction with Testo Lab Pro® to raise testosterone levels higher than with supplementing alone.

Take note that though many standard DAA supplements recommend cycling DAA 2-3 weeks “on” and 1-2 weeks “off,” Testo Lab Pro®’s minimally effective dosage of D-AA-CC requires no cycling and may be safely used daily for long-term male health and fitness enhancement.

Optimal D-Aspartic Acid Dosage

D-aspartic acid supplements ordinarily range anywhere from 1,000mg to 5,000mg dosages daily, often with requirements of splitting up the daily dosage into several smaller servings for greater dosage distribution and absorption throughout the day.

With D-AA-CC, the dosage requirement is smaller.

  • 600mg D-AA-CC daily is an effective dosage for safely and sustainably maintaining healthy levels of testosterone with minimal risk of side effect.

Research has found safe administration at 3,000mg, though 6,000mg DAA has been associated with lower T production.[5] But for D-AA-CC, the 600mg daily dosage is sufficient for safely boosting T.

Does D-Aspartic Acid Have Any Side Effects?

By stimulating the HPG axis, D-aspartic acid encourages greater production of FSH, LH, and testosterone.

For this reason, it's a much healthier method of testosterone boosting than that of, say, anabolic steroids, which simply flush the body with an inordinately high degree of synthetic testosterone activity.

As such, it’s rare for DAA to oversteer into “side effect” territory.

Even so, as with most supplements, natural or otherwise, taking excessive amounts of DAA may pose certain adverse side effect risks.

Some of the more commonly reported DAA side effects include:

  • Irritability and mood swings
  • DHT-influenced hair loss and acne
  • Estrogen-influenced gynecomastia and impaired libido

Granted, many of these side effects are rare and may be easily mitigated by pairing DAA with natural aromatase-blockers (estrogen blockers) and DHT-regulators (5-alpha reductase blockers).

However, it’s important to note that DHT is also an important male sex hormone, so refer to a physician before supplementing DAA, if DHT count is a health concern on your radar.

Either way, a smart testosterone booster formula, such as Testo Lab Pro®, will have already done the work for you to ensure that you acquire the male health benefits of DAA without the side effect risks.

Final Word on the Testosterone Benefits and Side Effects of D-Aspartic Acid

Because D-aspartic acid seems to boost sex hormone levels across the board, it’s important to stack this key male enhancer with complementary hormone regulating supplements. Such as luteolin (aromatase blocker) and ashwagandha extract (herbal adaptogen).

By pairing D-aspartic acid, as advanced D-AA-CC form, with other complementary natural testosterone boosters, Testo Lab Pro® maximizes the male health-boosting benefits of DAA while minimizing the amino’s potential downsides.

And with an all-natural, plant-based formula delivered in plant-based, prebiotic-infused NutriCaps® capsules, Testo Lab Pro® is also the safest and most effective natural, legal T-booster for men of all dietary lifestyles.


  1. Roshanzamir F, Safavi SM. The putative effects of D-Aspartic acid on blood testosterone levels: A systematic review. Int J Reprod Biomed. 2017 Jan; 15(1): 1-10.
  2. Plant TM. The hypothalamo-pituitary-gonadal axis. J Endocrinol. 2015 Aug; 226(2): T41-T54.
  3. Topo E et al. Evidence for the involvement of D-aspartic acid in learning and memory of rat. Amino Acids. 2010 May; 38(5): 1561-9.
  4. D’Aniello et al. D-Aspartate, a Key Element for the Improvement of Sperm Quality. Advances in Sexual Medicine. 2012; 2(4): 45-53.
  5. Melville GW et al. Three and six grams supplementation of d-aspartic acid in resistance trained men. J Int Soc Sports Nutr. 2015 Apr 1; 12: 15.
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