Preliminary research has suggested that luteolin may help with several chronic conditions. Though, one of the most notable benefits of luteolin is its effect on testosterone.

Though, as with any supplement in the early stages of research, there are possibly some downsides to consider.

Does luteolin have side effects? How much is too much? Is it safe to supplement with?

Read on to find out all you need to know about luteolin, including the health benefits, side effects, doses, and the best supplement to consider!

What is Luteolin?

Luteolin, not to be confused with lutein, is a flavonoid present in many colorful fruits, vegetables, and medicinal herbs.

The main role of flavonoids is to protect plants from microbes and other environmental threats, though they are also beneficial for humans as they potentially offer a variety of health benefits.

Many herbal traditions around the world utilize luteolin-rich plants to strengthen the immune system, relieve inflammation, and even help to fight cancer.

You can find luteolin in foods such as parsley, celery, dandelion, onion, citrus fruits, and some and vegetables.

Health Benefits of Luteolin

Some of the initial research on luteolin suggests that it may:

  • Possibly protect the brain and nerves

With this, luteolin is thought to potentially help a range of cognitive and brain-related conditions such as Alzheimer’s disease, depression, seizures, and brain trauma.

  • Possess antimicrobial properties

Having antimicrobial properties will help protect the body against bacterial and viral infections.

  • Promote heart health

Studies in mice suggest that luteolin may potentially decrease inflammation and fat buildup in blood vessels, thus protecting against atherosclerosis or plaque buildup. Though, research in this area is still in its youth.

  • Help reduce inflammation and allergies

Once again, in mice studies, luteolin has been shown to possibly prevent inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines.

  • Boost testosterone levels

One of the most commonly known benefits of luteolin is its impact on testosterone. Luteolin has been shown to block aromatase, which is the enzyme that converts testosterone (the male hormone) into estrogen (the female hormone).

In addition to this, luteolin’s bioactivity indirectly supports healthy testosterone levels, which is precisely why it’s one of the key ingredients in Testo Lab Pro.

So, to counter these health benefits, is there anything we need to be aware of when supplementing with luteolin? Let’s take a look!

Luteolin: Side Effects

At the time of writing, there have been no noted side effects of supplementing with luteolin, provided the supplements' dosage guidelines are followed.

However, luteolin supplements are not suitable for those who are pregnant, suffer from colitis, or who are children.

Otherwise, the studies so far have reported no harmful effects.

As with any supplement, it’s important to consult your doctor if you’re considering taking anything new!

Luteolin: Dosage

Luteolin is available in many different supplement forms, such as chewable tablets, powders, and pills.

Many product labels contain around 100-300mg of luteolin per serving, though doses of 60mg also appear to be effective.

While you can take luteolin as a standalone supplement (though it is usually paired with rutin, a flavonoid derived from quercetin), it is usually more beneficial to take it as part of a stack, particularly when taking it for testosterone.

The Best Luteolin Supplement

Following on from the above, luteolin is best taken as part of a stack, especially when taking it for boosting testosterone levels.

Our top pick is Testo Lab Pro. This formula stacks luteolin, sourced from natural orange fruit extract, with D-aspartic acid, a full-spectrum sex hormone booster.

Luteolin maximizes the effects of D-aspartic acid, helping to block the effects of aromatase, the enzyme that converts testosterone to estrogen.

Alongside this, Testo Lab Pro also contains key vitamins and minerals to help support overall male health, combined with herbal extracts such as ashwagandha and mucuna pruriens, helping to promote peak male vitality.


Luteolin is a flavonoid with a range of anti-inflammatory and antioxidant properties. It is found in food sources such as citrus fruits, leafy greens, cruciferous vegetables, and some spices.

In many animal-based studies, luteolin has been shown to potentially help protect the brain and nerves, boost cardiovascular health, help reduce inflammation and allergies, and promote healthy testosterone levels.

While the research on luteolin is still in its early days, there have yet to be any reported side effects. However, supplementing with luteolin is not recommended for those who are pregnant, those who have colitis, or for children.

As with any supplement, it’s important to consult your doctor if you’re thinking of taking anything new.

When it comes to supplementing with luteolin for boosting testosterone, it is most effective when taken as a formula.

Testo Lab Pro is our top pick, which is the cleanest, safest, and most effective testosterone-boosting formula on the market!